Cyprotex PLC
('Cyprotex' or 'the Company')
Partnership in the EC funded EU-ToxRisk consortium

Cyprotex PLC (AIM:CRX), a specialist ADME-Tox and Bioscience Contract Research Organisation, today announces that it will form part of the EU-ToxRisk consortium; a project funded by the European Commission to work on the integration of new concepts for regulatory chemical safety assessment. A total of 39 partners are involved in the consortium ranging from industry, academia, research institutes, contract research organisations and regulatory bodies.

The EU-ToxRisk project will start in January 2016 and run for 6 years. The project is funded by the European Commission through its Horizon 2020 programme for Research and Innovation and has a total value to all partners of €30 million over 6 years. The award to Cyprotex is anticipated to be worth approximately €1.0 million over the 6 year period. The aim of the project is to develop new cutting-edge human relevant in vitro non-animal methods and in silico computational technologies for the early assessment of potential toxicity in humans. The ultimate goal is to provide the basis of future regulatory chemical safety testing using animal-free approaches for hazard and risk assessment. Cyprotex plays a major role in the delivery of absorption, distribution, metabolism and excretion (ADME) data to the consortium and will also be involved in validation of some of the newly developed toxicity models.

Anthony Baxter PhD, Chief Executive Officer of Cyprotex, comments, 'We are delighted to be part of the EU-ToxRisk consortium. The project is very much in line with the ethos of the Company where we have been developing in vitro and in silico methods for predicting human outcome for over 16 years. Animal testing is notoriously poor at predicting human safety for certain types of toxicity and awareness of the ethical issues associated with animal testing is growing rapidly. Developing more sophisticated human relevant models will help in addressing these issues, as well as improving the speed and efficiently of screening.'

For more information, download the official press release issued by the consortium here

For further information:

Cyprotex PLC
Tel: +44 (0) 1625 505 100
Dr Anthony Baxter, Chief Executive Office
John Dootson, Chief Financial Officer
Mark Warburton, Chief Operating Officer and Legal Counsel
ir@cyprotex.com
www.cyprotex.com

N+1 Singer (Nomad and broker to Cyprotex)
Tel: +44 (0)20 7496 3000
Shaun Dobson
shaun.dobson@n1singer.com
 Jen Boorer
jennifer.boorer@n1singer.com
www.nplus1singer.com

Cyprotex PLC

Cyprotex is listed on the AIM market of the London Stock Exchange (CRX). It has sites at Macclesfield and Alderley Park, both of which are near Manchester in the UK, and at Watertown, MA and Kalamazoo, MI in the US. The Company was established in 1999 and works with more than 1200 partners within the pharmaceutical and biotech industry, cosmetics and personal care industry and the chemical industry. Cyprotex acquired Apredica and the assets of Cellumen Inc. in August 2010 and the combined business provides support for a wide range of experimental and computational ADME-Tox and PK services. The acquisition of the assets and business of CeeTox in January 2014 has enabled Cyprotex to expand its range of services to target the personal care, cosmetics and chemical industries. In 2015, Cyprotex launched its new bioscience division to expand its capabilities into phenotypic and target based screening. The Company's core capabilities include high quality in vitro ADME screening services, in vitro bioscience services, mechanistic toxicology and high content toxicology screening services, including our proprietary CellCiphr® toxicity prediction technology, predictive modelling using PBPK and QSAR techniques, including Cloe® PK for in vivo PK prediction, and a range of skin, ocular and endocrine disruption services. For more information, see www.cyprotex.com.

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