Fulham will play hosts at Craven Cottage as rivals Queens Park Rangers make the trip across town this Saturday lunchtime.
Marco Silva's side have enjoyed a largely encouraging start to the season but will be determined to bounce back following a 4-1 defeat against Coventry City before the international break.
As for Mark Warburton's side, it has been a campaign that has got off to an excellent start with QPR sitting in sixth position in the table.
However, a west London derby will surely be a big test for the Hoops as they target a potential play-off finish.
Fulham v QPR: talkSPORT commentary
The Championship fixture is scheduled to take place on Saturday, October 16 with a kick-off time of 12.30pm.
talkSPORT 2 will have live coverage from Craven Cottage with Alex Crook and David Connolly which will get underway at 12pm.
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Upcoming talkSPORT commentaries
SATURDAY 16th OCTOBER
- Watford v Liverpool - 12:30, Premier League - talkSPORT EXCLUSIVE
- Fulham v QPR - 12:30, Championship - talkSPORT 2 EXCLUSIVE
- Southampton v Leeds United - 15:00, Premier League - talkSPORT 2 EXCLUSIVE
- Brentford v Chelsea - 17:30, Premier League - talkSPORT EXCLUSIVE
SUNDAY 17th OCTOBER
- Swansea v Cardiff - 12:00, Championship - talkSPORT 2 EXCLUSIVE
TUESDAY 19th OCTOBER
- Club Brugge v Manchester City - 17:45, Champions League - talkSPORT 2
- Stoke v Bournemouth - 19:45, Championship - talkSPORT 2 EXCLUSIVE
- Atletico Madrid v Liverpool - 20:00, Champions League - talkSPORT
WEDNESDAY 20th OCTOBER
- Spartak Moscow v Leicester - 15:30, Europa League - talkSPORT 2
- Swansea v West Brom - 19:45, Championship - talkSPORT 2 EXCLUSIVE
THURSDAY 21st OCTOBER
- Vitesse Arnhem v Tottenham - 17:45, Europa Conference League - talkSPORT 2
- Rangers v Brondby - 20:00, Europa League - talkSPORT 2 EXCLUSIVE
Fulham v QPR: Team news
Fulham: Rodak, Odoi, Ream, Adarabioyo, Bryan, Reed, Seri, Ivan Cavaleiro, Wilson, Kebano, Mitrovic.
Subs: Cairney, Chalobah, Reid, Rodrigo Muniz, Gazzaniga, Mawson, Robinson.
QPR: Dieng, Dickie, De Wijs, Barbet, Odubajo, Ball, Johansen, McCallum, Chair, Willock, Austin.
Subs: Amos, Dykes, Archer, Gray, Dunne, Adomah, Duke-Mckenna.
Referee: Oliver Langford
Fulham v QPR: What has been said?
Mark Warburton will miss the weekend's clash after testing positive for COVID-19.
He told the club website: "I tested positive after feeling unwell.
“Thankfully, I am double-jabbed and now appear to be over the worst of it.
“My time off last week coincided with the players having a pre-agreed few days off going into the international break.
“This week will see John Eustace prepare the squad for Saturday’s game at Fulham. I have been in regular contact with John and will continue to be so until I resume my normal duties at the end of the week.”
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