20 prescription drugs on Colorado’s affordability radar

DENVER (KDVR) — The Colorado board created to review prescription drug prices is headed to court after it moved to cap the price of arthritis medication Enbrel — and it’s not the only drug on the board’s radar.

Pharmaceutical company Amgen filed a federal lawsuit last week against the Colorado Prescription Drug Affordability Board, which in February declared Enbrel unaffordable. The drugmaker argues the move was unconstitutional and violates commerce and patent laws.

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Enbrel is not the first prescription drug that went under review, and it will not be the last. The board has also found that two other drugs — the HIV treatment Genvoya and the cystic fibrosis drug Trikafta — were not unaffordable. Next up for review are Cosentyx, for psoriasis, and Stelara, for Crohn’s disease.

What other drugs could be under the microscope next?

Top 20 drugs on Colorado drug affordability board’s list

The board’s most recent report from October listed 604 drugs eligible for an affordability review. Some 244 were prioritized on a weighted scale based on the number of patients, the change in wholesale acquisition cost, patient out-of-pocket cost, total paid and average paid per person per year.

The list is neither binding nor required by law and is instead “meant to be a tool to present data and spark discussion,” according to the board.

Here are the top 20 listed:

Brand Name

Strength

Dosage Form

Patient Out-of-Pocket Cost

Humira

40 mg/0.4 mL

Pen injector kit

$2,982

Trikafta

100 mg-50 mg-75 mg (day)/150 mg (night)

Tablet sequential

$1,732

Enbrel

50 mg/mL (1 mL)

Pen injector

$2,812

Stelara

90 mg/mL

Syringe

$1,399

Humira

40 mg/0.4 mL

Syringe kit

$2,556

Genvoya

150 mg-150 mg-200 mg-10 mg

Tablet

$1,293

Aubagio

14 mg

Tablet

$4,207

Gilenya

0.5 mg

Capsule

$3,367

Xtandi

40 mg

Capsule

$3,078

Revlimid

10 mg

Capsule

$3,232

Imbruvica

420 mg

Tablet

$3,308

Enbrel

50 mg/mL (1 mL)

Syringe

$2,709

Cosentyx

150 mg/mL

Pen injector

$2,168

Takhzyro

300 mg/2 mL (150 mg/mL)

Vial

$4,999

Ibrance

125 mg

Tablet

$1,862

Opdivo

240 mg/24 mL

Vial

$1,001

Norditropin

15 mg/1.5 mL (10 mg/mL)

Pen injector

$3,398

Entyvio

300 mg

Vial

$2,447

Epclusa

400 mg-100 mg

Tablet

$1,887

Opsumit

10 mg

Tablet

$2,594

These are just the top 20 on the priority list, some of which have already gone under review. See the full list on the Colorado Prescription Drug Affordability Board’s dashboard.

Could Colorado limit prescription drug price caps?

The Prescription Drug Affordability Board was created in 2021 to review prescription drugs and evaluate their affordability for Coloradans, and it has the legal authority to cap prices. But this session, lawmakers are considering a bill to limit which prescription drugs can get price caps.

Senate Bill 24-060 would exempt so-called “orphan drugs.” These are medications designated as such because they treat a rare disease or condition, typically one that affects fewer than 200,000 people in the U.S.

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Supporters of the bill argue this is about relatively few drugs for very rare conditions. Opponents are concerned that some of these drugs have multiple uses.

The bill passed out of a Senate committee but has been laid over three times since. Its next scheduled floor date is April 1.

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