Rob Lowe and Sheryl Berkoff's Relationship Timeline

1983: Robe Lowe and Sheryl Berkoff go on a blind date

Rob Lowe and Sheryl Berkoff's love story began after a blind date in 1983; however, the pair didn't begin a romantic relationship until 1989, when they worked together on Lowe's 1990 thriller Bad Influence. At the time, Berkoff was a renowned makeup artist.

1989: Rob Lowe and Sheryl Berkoff begin casually dating

Despite feeling a strong connection after reconnecting on the set of Bad Influence, Lowe had trouble opening up in a meaningful way.

"Intimacy and I were not very well acquainted until very late in my life," he told PEOPLE in January 2022.

He credited Berkoff as a big reason for his recovery from addiction, saying, "I had the feeling that if I was ever going to be able to make it work with anybody, it was Sheryl. Alcohol and drugs were only going to make that next to impossible."

Early 1990s: Rob Lowe says he's "really lucky" to have met Sheryl Berkoff when he did

It was not the first time the actor credited his wife with saving his life, telling Entertainment Tonight in May 2021, "Listen, she may have saved my life, really. I mean, she met me when I was at the end of my '80s run of wild boy craziness, and she was worth changing my life for."

He continued, "And so I am really lucky that that happened to me. Maybe I had changed it on my own, maybe, but it's a big maybe. And just when I met her, I knew that if I could not make it with her, I definitely could not make it work with anyone else."

July 22, 1991: Rob Lowe and Sheryl Berkoff marry

The pair wed on July 22, 1991. Lowe spoke candidly about Berkoff being the right person for him on Gwyneth Paltrow's Goopfellas podcast in 2019.

"It really is all about who you pick," he said. "I always say to people, 'If there's any way to marry your best friend, do it.' Cause the rest of it comes and goes, and I was very lucky there."

September 24, 1993: Rob Lowe and Sheryl Berkoff welcome their first child together

In 1993, the couple welcomed their first son, Matthew, into the world. Reflecting on his journey through parenthood, Lowe told PEOPLE, "I'm happy I lived the life that I lived because I have no regrets, but I was super ready to coach Little League, carve pumpkins on Halloween, read books and serve hot lunch on Wednesdays. I really, really loved every minute of it."

November 6, 1995: Rob Lowe and Sheryl Berkoff welcome a second son

Lowe and Berkoff welcomed their second child, John Owen, in 1995. Reflecting on the role of his parents in his life, John Owen told PEOPLE in January 2022, "He was always there for me. I credit that with being one, if not the main, reason that I'm sober and living a healthy lifestyle."

John Owen also followed in his father's footsteps with acting and producing. The father-son duo are set to star on Netflix's comedy series Unstable in 2022, where they will both serve as co-creators and executive producers.

1994: Rob Lowe and Sheryl Berkoff hit the red carpet together

In 1994, the pair attended the premiere of True Lies together.

March 31, 1995: Rob Lowe and Sheryl Berkoff attend the 'Tommy Boy' premiere

In 1995, the couple was all smiles as they arrived at the premiere of Tommy Boy.

October 25, 1996: Rob Lowe and Sheryl Berkoff get dressed up for charity

Berkoff and Lowe looked dashing while attending the Carousel of Hope Ball in L.A. in October 1996.

July 11, 1997: Rob Lowe and Sheryl Berkoff attend the premiere of 'Contact'

In 1997, the pair rocked casual looks on the red carpet for the premiere of Contact.

June 11, 1999: Rob Lowe and Sheryl Berkoff show PDA on the red carpet

The two shared a bit of PDA while attending the 1999 premiere of Austin Powers: The Spy Who Shagged Me in L.A.

January 21, 2001: Rob Lowe and Sheryl Berkoff attend the Golden Globes together

The lovebirds brought date night to the red carpet in 2001 when they attended the Golden Globes together.

March 25, 2001: Rob Lowe and Sheryl Berkoff attend Oscar afterparty together

Another day, another party! The couple worked all-black looks to the Vanity Fair Oscar Party in 2001.

March 10, 2002: Rob Lowe and Sheryl Berkoff attend SAG Awards together

Berkoff rocked a sexy sheer number while accompanying her hubby to the 2002 SAG Awards.

March 27, 2011: Rob Lowe and Sheryl Berkoff get glam for the Oscars

Though the pair often steps out for big events together, they mostly keep their relationship private. Here, they posed at the 2011 Vanity Fair Oscar Party.

December 9, 2015: Sheryl Berkoff and sons support Rob Lowe at Hollywood Walk of Fame ceremony

The whole family was on hand to celebrate Lowe receiving a star on the Hollywood Walk of Fame in 2015.

Lowe's son Matthew said that his father is "great with relationship advice." Elaborating to PEOPLE he explained, "He'll say, 'When I found your mother, I knew she was the one. I married my best friend, and it's worked out perfectly for me. So take that advice.' ... He gives little pearls of wisdom like that that I keep with me. Hopefully, I will end up in a 30-year marriage like him."

February 22, 2015: Rob Lowe and Sheryl Berkoff get dressed up for 'Vanity Fair' Oscar party

In 2015, the couple once again got all dressed up for the Vanity Fair Oscar party.

October 18, 2016: Rob Lowe calls Sheryl Berkoff his best friend

"Somebody asked Alfred Hitchcock what makes a movie great, and he said, 'It's all casting. It's 100 percent casting.' And I think marriage is the same way. It's who you choose," Lowe told Rachael Ray in 2016.

When asked why he chose Berkoff, he said, "She's my best friend ... and she's hot. Hot, best friend, done."

June 6, 2021: Rob Lowe and Sheryl Berkoff appear on 'Family Feud'

In 2021, Lowe surprised his wife — who is a huge fan of Family Feud — by getting their family on the show in honor of her birthday.

"The producers were telling me this — they said it was your birthday, it was your whole dream you wanted to be on the show, so Rob made it happen," said host Steve Harvey.

January 19, 2022: Rob Lowe expresses his gratitude for Sheryl Berkoff and their family

"Up until I turned 26, I spent all my time investing in my career. From 26 on, I've invested in me," Rob Lowe told PEOPLE in his January 2022 cover story.

He added, "I've never been happier, personally or professionally [and] there's not a day that goes by where I'm not thankful about it all."

2022: Sheryl Berkoff celebrates career as jewelry designer with Rob Lowe's support

During the launch of her new website in 2022, Berkoff shared details on making the career switch from makeup artist to fine jewelry designer and owner of Sheryl Lowe Jewelry. She even has a line inspired by her husband and sons, aptly named Mr. LOWE.

July 22, 2022: Rob Lowe and Sheryl Berkoff celebrate 31st wedding anniversary

On their 31st wedding anniversary, Lowe honored his "partner in love" on Instagram.

"Happy 31st Anniversary, baby," he wrote. "Your love has made my world. You are as beautiful, knowledgeable, fascinating, kind, and hilarious as you were so many glorious years ago."

The actor previously told PEOPLE that, after more than three decades together, he still thinks Berkoff is "the hottest, sexiest, most beautiful, insane, complicated, entertaining person" he's ever known, adding that she's a "great mother."

March 23, 2023: Sheryl Berkoff supports Rob Lowe and son John Owen at premiere of 'Unstable'

Berkoff joined Lowe and John Owen on the red carpet at the Los Angeles premiere of their Netflix series Unstable. The show follows Jackson Dragon, played by John Owen, who goes to work for his eccentric father — Lowe's character, Ellis Dragon.

Berkoff and Lowe's eldest son, John Owen, was also present for the special family outing.

July 22, 2023: Sheryl Berkoff and Rob Lowe celebrate 32 years of marriage

In honor of their wedding anniversary, Lowe penned a sweet post about Berkoff on Instagram.

"Today marks 32 years married to this beautiful, inspiring, nurturing, strong, industrious, sexy, and wonderfully unique woman," he captioned a selfie of his wife. "I am SO grateful for the day she said she’d join me on our amazing life journey together. Happy Anniversary, Baby!!"

April 13, 2024: Sheryl Berkoff and Rob Lowe attend the Breakthrough Prize Honors Ceremony

The couple joined celebrities such as Kim Kardashian, Jessica Chastain and Bradley Cooper at the Breakthrough Prize Honors Ceremony in Los Angeles. Both Berkoff and Lowe wowed in all-black ensembles.