In mammalian reproduction, oocyte development begins before birth ... granulosa cells display modifications in distal regulatory elements. The orphan nuclear receptor, liver receptor homolog-1, is ...
In this study, we observed that a low level of fetal bovine serum (FBS) effectively induced DA neurons in rat neural ...
DUR-928 is a small molecule drug that modulates the activity of various nuclear receptors involved in liver homeostasis (stable function). It is under development for the potential treatment ...
Nuclear transport receptors (NTRs) are the only proteins able to transport ... More importantly, through the development of a novel bait-prey proteomic approach, we show that the non-classical NTR ...
“The nuclear hormone receptor gene, NR2E3 ... The FDA Office of Orphan Products Development grants orphan designation for novel drugs or biologics that treat a rare disease or condition ...
We showed that in OA cartilage the increased abundance of many proteins, including extracellular matrix protein Fibronectin (Fn1) and an orphan nuclear receptor Nr4a1 is translationally ... the loss ...
The nuclear receptor RORγt is believed to be the ... the restoration of the intestinal barrier function. Immunic's lead development program, IMU-838, is in phase 2 clinical development for ...
Inventiva is a clinical-stage biopharmaceutical company focused on the development of oral small ... in the domain of ...
Unopposed estrogen production and obesity are the most common risk factors for the development of endometrial cancer ...
Inventiva is a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies ... expertise and experience in the domain of compounds targeting nuclear receptors, ...
The development of drugs such as heparin ... The imaging segment is segmented into electrocardiogram (ECG), echocardiogram, nuclear scan, coronary angiography, and cardiac CT scan. The treatment ...
The process of apomictic seed development in land plants consists of three distinct ... and a candidate male reproductive ...