Growth factors activate mTOR complex 2 (mTORC2) through poorly defined mechanisms to modulate cell metabolism. In this issue ...
1 Center of Medical and Health Analysis, Peking University Health Science Center, Beijing 100191, China. 2 Neuroscience ...
1 Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA. 2 ...
1 Graduate School of Life Science, Hokkaido University, Sapporo, Japan. 2 Faculty of Sciences, Hokkaido University, Sapporo, ...
1 Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695, USA. 2 Department ...
1 National Institute of Biological Sciences, Beijing, No. 7 Science Park Road, Zhongguancun Life Science Park, Beijing 102206 ...
Deciphering how macrophages are reprogrammed in disease may lead to better patient therapies. Inflammation and metabolic stress are associated with diseases other than cancer, notably critical ...
1 Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. 2 Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, IL ...
1 Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University,106 91 Stockholm, Sweden. 2 The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå Centre for ...
1 Institut Pasteur, Unité de Microbiologie Structurale, CNRS UMR 3528 & Université Paris Diderot, 25 Rue du Docteur Roux, 75724 Paris Cedex 15, France. 2 Institut Pasteur, Plateforme de Biophysique ...
A viral EGF homolog increases the migration of cells infected with vaccinia virus to promote viral spread. Virally encoded effector proteins can increase the motility of infected cells to promote ...
Systems analysis shows that RNA-binding proteins are critical for Sindbis virus infection. Viral infection stimulates global mRNA translational arrest, and the detection of viral nucleic acids ...