A dihydropteroate synthetase inhibitor is a drug that ... antibacterial sulfonamides act as competitiveinhibitors of the ... (4-): Amodiaquine # • Chloroquine # (8-): Primaquine # • ...
The reductant N-methyldihydronicotinamide and the inhibitorprimaquine bind exclusively to the ... Binding, Competitive; Chloroquine/pharmacology; Copper/analysis; Humans; Kinetics
The addi-tionof2-deoxyglucose, a competitiveinhibitor of glucose metabolism (18), partially protected the red cells from primaquine action. Depletion of endogenous substrates by ...
Inhibitors of alternative alleles of genes encoding ... A "competitive" inhibitor is one that binds to the same site on the ... variances account for sensitivity to primaquine and ...
... the N-N CH 3 O HO N N HN N Cl N OCH 3 HN NH 2 Quinine Chloroquine Primaquine ... An obvious requirement for a competitive protease inhibitor is that the substance cannot be hydrolysed ...
The intrinsic activity of the non-competitiveinhibitor is actually a negative number. Note ... potent drug induces the same response at a lower concentration. Primaquine ...
Evaluation of chemicals as inhibitors of trout cytochrome ... 60 min preincubation the inhibition remains non-competitive ... and rabeprazole and the anti-malaria drug primaquine were ...