SV40 - Wikipedia
WebSV40 is an abbreviation for simian vacuolating virus 40 or simian virus 40, a polyomavirus that is found in both monkeys and humans. Like other polyomaviruses, SV40 is a DNA virus that sometimes causes tumors in animals, but most often persists as a latent infection.
Emergent Human Pathogen Simian Virus 40 and Its Role in Cancer
WebThe polyomavirus simian virus 40 (SV40) is a known oncogenic DNA virus which induces primary brain and bone cancers, malignant mesothelioma, and lymphomas in laboratory animals. Persuasive evidence now indicates that SV40 is causing infections in humans today and represents an emerging pathogen.
Vaccine Ingredients – SV40 | Children's Hospital of Philadelphia
WebApr 28, 2020 · Vaccine Ingredients – SV40. Polio vaccines used in the late 1950s and early 1960s were contaminated with a virus called simian virus 40 (SV40) present in monkey kidney cells used to grow the vaccine. Subsequently, investigators found SV40 DNA in biopsy specimens obtained from patients with cancers such as mesothelioma (lung), …
Association Between Simian Virus 40 and Human Tumors - PMC
WebJul 25, 2019 · Simian virus 40 (SV40) is a small DNA tumor virus of monkey origin. This polyomavirus was administered to human populations mainly through contaminated polio vaccines, which were produced in naturally infected SV40 monkey cells.
Simian virus 40 in humans - Infectious Agents and Cancer
WebJul 9, 2007 · Simian virus 40 (SV40) is a monkey virus that was administered to human populations by contaminated vaccines which were produced in SV40 naturally infected monkey cells.
SIMIAN VIRUS 40 - Malaria and Some Polyomaviruses (SV40, BK, …
WebThe inability of SV40 to complete its life-cycle and lyse infected cells from some species can have important biological consequences. For example, non-permissive mouse and rat cells can survive SV40 infection and go on to be stably transformed by the virus.
Cell and Molecular Biology of Simian Virus 40: Implications for …
WebJan 20, 1999 · SV40 is a potent DNA tumor virus that induces tumors in rodents and transforms many types of cells in culture, including those of human origin. This virus has been a favored laboratory model for mechanistic studies of molecular processes in eukaryotic cells and of cellular transformation.
Conventional epidemiology and the link between SV40 and
WebThe main types of tumour induced by SV40 in laboratory animals mirror the human cancers that have been found to contain SV40 DNA or the viral oncoprotein. Increasing amounts of data support the notion that SV40 may be an aetiological factor in the development of human cancers.
SV40 and human tumours: myth, association or causality?
WebDec 1, 2002 · SV40, JCV and BKV share about 70% sequence similarity and can be distinguished at the nucleic-acid level. SV40 is of monkey origin, but has been identified in a select group of human tumours.
SV40 – An Obscure Monkey Virus and the Golden Age of
WebMar 1, 2022 · SV40, which stands for simian virus number 40, is scientifically a highly influential virus yet it is largely unknown to the general public. From 1960 to 2020 this small virus appeared in over 20,000 publications.
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