A pharmaceutical CEO is pondering thefts and irregularities at his company. He drinks a drug that temporary suppresses his signs and gives him a deathlike state for a couple of days. Something goes wrong. His daughter and he have had a rocky relationship, but she attempts to rescue him with help from a company employee.

An outbreak of dog flu has spread through the city of Megasaki, Japan, and Mayor Kobayashi has demanded all dogs to be sent to Trash Island. On the island, a young boy named Atari sets out to find his lost dog, Spots, with the help of five other dogs... with many obstacles along the way.