Chicago is the most populous city in the U.S. state of Illinois and the third most populous in the …Chicago is the most populous city in the U.S. state of Illinois and the third most populous in the United States after New York City and Los Angeles. With a population of 2,746,388 in the 2020 census, it is also the most populous city in the Midwest. As the seat of Cook County, the city is the center of the Chicago metropolitan area, one of the largest in the world.
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