Bigbee Valley is an unincorporated community in Noxubee County, Mississippi, United States. Variant names are "Bigbeevale", "Nances Mill", and "Whitehall". Bigbee Valley is located on Mississippi Highway 388, 2.4 mi west of the Alabama state line. The hamlet was historically located near the west bank of the Tombigbee River. The construction of the Tennessee–Tombigbee Waterway in 1984 moved the navigable portion of the waterway 4.0 mi east.
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