Houston Acres is a home rule-class city in Jefferson County, Kentucky, United States. The population was 507 at the 2010 census. Houston …Houston Acres is a home rule-class city in Jefferson County, Kentucky, United States. The population was 507 at the 2010 census. Houston Acres is located in east-central Jefferson County. It is bordered to the west by Louisville, to the north by Cambridge, and on its remaining sides by consolidated Louisville/Jefferson County. Kentucky Route 155 runs along the northern border of the city, leading west 2 miles to Interstate 264 and east 1.5 miles to Forest Hills. Downtown Louisville is 8 miles northwest of Houston Acres.