Salisbury is a city in and the county seat of Wicomico County, Maryland, United States. Salisbury is the largest city in the state's Eastern Shor…Salisbury is a city in and the county seat of Wicomico County, Maryland, United States. Salisbury is the largest city in the state's Eastern Shore region, with a population of 33,050 at the 2020 census. Salisbury is the principal city of the Salisbury, Maryland-Delaware Metropolitan Statistical Area. The city is the commercial hub of the Delmarva Peninsula, which was long devoted to agriculture and had a southern culture. It calls itself "The Comfortable Side of Coastal".
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