Saltillo is an unincorporated community in Hopkins County, Texas, in the United States. It is located sixteen miles east of Sulphur Springs at th…Saltillo is an unincorporated community in Hopkins County, Texas, in the United States. It is located sixteen miles east of Sulphur Springs at the intersection of US 67 and FM 900. Saltillo has a population of approximately 300. Despite being unincorporated, Saltillo has its own post office, assigned the ZIP code of 75478. The community's school system: the Saltillo Independent School District serves area students.
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