Mitochondria-targeted Antioxidant Effects of S(-) and R(+) Pramipexole

Conclusions

These results support the concept of both S(-) and R(+) pramipexole enantiomers as mitochondria-targeted antioxidants and suggest that the antioxidant, neuroprotective activity of these drugs is independent of both the chiral 6-propylamino group in the pramipexole molecule and the DA receptor stimulation.

BMC Clin Pharmacol. 2010;10:1-6. © 2010  other

Cite this: Mitochondria-targeted Antioxidant Effects of S(-) and R(+) Pramipexole - Medscape - Feb 05, 2010.