Tweaking Gene Expression to Repair Lungs (IMAGE) University of Pennsylvania School of Medicine Caption This graphic shows the expression of the important transcription factor Sox2 (green staining and outlined with dashed line) in the airway epithelium of control mouse lung airways (A). Loss of Hdac1/2 expression leads to loss of Sox2 expression in Hdac1/2 double knockout animals (B). Credit Ed Morrisey, Ph.D., Perelman School of Medicine, University of Pennsylvania. Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.