Tennessee Titans vs. Buffalo Bills picks, predictions: Who wins NFL Week 2 game?
Jeremy CluffThe Tennessee Titans and Buffalo Bills play on Monday, Sept. 19 in an NFL Week 2 game.
Which team will get the victory?
Check out these NFL Week 2 picks and predictions for the game, which can be seen at 4:15 p.m. MST on ESPN.
The Bills are a 9.5-point favorite in the game.
NFL Week 2 picks, predictions:
- Chargers vs. Chiefs | Dolphins vs. Ravens | Jets vs. Browns
- Commanders vs. Lions | Colts vs. Jaguars | Bucs vs. Saints
- Panthers vs. Giants | Patriots vs. Steelers | Falcons vs. Rams
- Seahawks vs. 49ers | Bengals vs. Cowboys | Titans vs. Bills
- Cards vs. Raiders | Bears vs. Packers | Texans vs. Broncos
- Vikings vs. Eagles | The Republic's Week 2 NFL predictions
The Arizona Republic: Bills 38, Titans 24
Jeremy Cluff writes: "The Titans will definitely be motivated after losing to the Giants in Week 1. Being motivated won't be enough against the Bills."
Bookies.com: Take the under in Titans vs. Bills game
Bill Speros writes: "The Bills are coming off an extended break following their Week 1 Thursday night rout of the Rams. Expect a raucous and well-lubricated crowd in Buffalo. Many will be bruised not beaten following a bevy of table swoons in the parking lot. The Titans got KO’d at home in the Divisional Round. More importantly, they did not improve much in the offseason, as was evidenced Sunday against the Giants. The line is moving in the wrong direction. We locked in the under at 51 before the Titans fizzled against the Giants. It has since moved to 49.5. So if you missed that window, look for the Bills to score the big-time cover at home for your NFL Week 2 best bets."
- Chargers vs. Chiefs | Dolphins vs. Ravens | Jets vs. Browns
- Commanders vs. Lions | Colts vs. Jaguars | Bucs vs. Saints
- Panthers vs. Giants | Patriots vs. Steelers | Falcons vs. Rams
- Seahawks vs. 49ers | Bengals vs. Cowboys | Titans vs. Bills
- Cards vs. Raiders | Bears vs. Packers | Texans vs. Broncos
- Vikings vs. Eagles | Spreads, lines, point totals | Super Bowl
Draft Kings: Bills will cover in game vs. Titans
It writes: "Allen and the Bills looked unstoppable against a team coming off a Super Bowl win. A team coming off a Giants loss — Derrick Henry or no Derrick Henry — should be quick work for them, especially if the defensive line can keep the same pressure up on Monday against Tannehill that they brought last Thursday."
ESPN: Bills have a 81.1% chance to win the game
The site's Football Power Index gives the Titans an 18.7 % shot at picking up the victory.
More:NFL Week 2 schedule, television information: How to watch Week 2 NFL games
Pro Football Network: Take the Bills against the spread vs. Titans
BJ Rudell writes: "As alluded to above, the AFC South remains wide open, and the outlook probably will remain foggy after this next slate of games. That’s because Tennessee will face the first of its many (yes, many) brutally tough opponents — a big reason why I picked them not to win their division this year. Barring something unforeseen, Buffalo should win by 18+."
Vegas odds: Go with the Bills to cover vs. Titans
Annie Adkins writes: "The Bills are going to win this game, we have no doubts about it. And they’re going to do it by a big margin, covering the spread along the way. Still, we do expect the Titans to do well rushing-wise, with Henry probably scoring a TD or two."
More:NFL power rankings Week 2: Cardinals, Bengals, Patriots, Packers plummet after Week 1 losses
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on Twitter @Jeremy_Cluff.
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