Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Salk scientists explain how CBN protects the brain against aging and neurodegeneration

One in every 10 individuals above the age of 65 develops an age-related neurological disorder like Alzheimer's or Parkinson's, yet treatment options remain sparse for this population.

17 Apr 2024

AI techniques massively accelerate the search for Parkinson's disease treatments

Researchers have used artificial intelligence techniques to massively accelerate the search for Parkinson's disease treatments.

17 Apr 2024

ELRIG UK and SRG announce partnership to advance life science professionals in drug discovery

The European Laboratory Research & Innovation Group (ELRIG) UK, a not-for-profit, volunteer-led organization for the drug discovery community, today entered into a partnership with SRG, leaders in life science recruitment, to support the advancement of science professionals in their careers.

From ELRIG (UK) Ltd. 17 Apr 2024

MD Anderson and CureVac collaborate on mRNA-based cancer vaccines

The University of Texas MD Anderson Cancer Center and CureVac N.V. today announced a co-development and licensing agreement to develop novel mRNA-based cancer vaccines.

16 Apr 2024

Deciphering the molecular interactions of opioid receptors: Implications for drug design

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl.

13 Apr 2024

Insilico Medicine's AI-driven approach yields promising PTPN2/N1 inhibitor for cancer immunotherapy

In recent years, cancer immunotherapy, exemplified by PD-1 and its ligand PD-L1 blockade, has made remarkable advances.

13 Apr 2024

Blocking polyphosphates could help treat chronic infections

Most disease-causing bacteria are known for their speed: In mere minutes, they can double their population, quickly making a person sick.

12 Apr 2024

Metrion Biosciences enhances High Throughput Screening services with access to Enamine compound libraries

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From Metrion Biosciences Limited 11 Apr 2024

Research identifies how leukemia develops resistance to first line treatments

Relapses in a common form of leukemia may be preventable following new research which has identified how the cancer develops resistance to first line treatments.

9 Apr 2024

Therapeutic potential of CD20 x CD3 bispecific antibodies

On Monday, March 25th, 2024, the U.S. FDA declined approval for Regeneron’s Odronextamab for two forms of lymphoma due to concerns over the progress of ongoing confirmatory trials.

From Sino Biological Inc. 5 Apr 2024

Using brain organoids to unlock TBI's link to dementia and ALS

A traumatic brain injury (TBI) can quadruple your risk for developing dementia and increase your chances of developing neurodegenerative diseases such as ALS.

4 Apr 2024

Atomic-level structural models of enzymes provide disease insights

When nucleic acids like DNA or RNA build up in a cell's cytoplasm, it sets off an alarm call for the immune system.

2 Apr 2024

Generative AI revolutionizes antibiotic development against resistant pathogens

With nearly 5 million deaths linked to antibiotic resistance globally every year, new ways to combat resistant bacterial strains are urgently needed.

28 Mar 2024

Researchers discover a safer and more efficient technique for testing new drugs

McGill researchers have discovered a safer and more efficient technique for testing new drugs while they are in development.

28 Mar 2024

Synthetic gut lining developed for microbiome research

A team of Penn State researchers has developed a new synthetic material that could enable scientists to more easily study how microorganisms interact with the gastrointestinal (GI) system.

28 Mar 2024

AI-powered method predicts protein dynamics to accelerate drug discovery

Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them.

27 Mar 2024

Ubiquigent and Debiopharm enter agreement to support USP1 inhibitor programme for Debio 0432

Project will be a demonstration of how Ubiquigent’s DUB-centric platform can support the development of DUB inhibitors all the way from discovery through to clinical development.

From Ubiquigent Limited 26 Mar 2024

Leveraging cancer therapies to combat tuberculosis

What could cancer teach us about tuberculosis? That's a question Meenal Datta has been chasing since she was a graduate student.

25 Mar 2024

bioXcelerate launches breakthrough AI tool for faster drug discovery

bioXcelerate, a new and innovative health data science division of Optima Partners Limited, has revealed a new groundbreaking AI tool, which is set to accelerate the process for identifying and developing new drugs.

24 Mar 2024

Researchers create new platform to identify proteins for targeted treatment of disease

Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins -; a new but largely unrealized approach to the treatment of disease.

22 Mar 2024

Drug Discovery News and Research

Further Reading

Salk scientists explain how CBN protects the brain against aging and neurodegeneration

AI techniques massively accelerate the search for Parkinson's disease treatments

ELRIG UK and SRG announce partnership to advance life science professionals in drug discovery

MD Anderson and CureVac collaborate on mRNA-based cancer vaccines

Deciphering the molecular interactions of opioid receptors: Implications for drug design

Insilico Medicine's AI-driven approach yields promising PTPN2/N1 inhibitor for cancer immunotherapy

Blocking polyphosphates could help treat chronic infections

Metrion Biosciences enhances High Throughput Screening services with access to Enamine compound libraries

Research identifies how leukemia develops resistance to first line treatments

Therapeutic potential of CD20 x CD3 bispecific antibodies

Using brain organoids to unlock TBI's link to dementia and ALS

Atomic-level structural models of enzymes provide disease insights

Generative AI revolutionizes antibiotic development against resistant pathogens

Researchers discover a safer and more efficient technique for testing new drugs

Synthetic gut lining developed for microbiome research

AI-powered method predicts protein dynamics to accelerate drug discovery

Ubiquigent and Debiopharm enter agreement to support USP1 inhibitor programme for Debio 0432

Leveraging cancer therapies to combat tuberculosis

bioXcelerate launches breakthrough AI tool for faster drug discovery

Researchers create new platform to identify proteins for targeted treatment of disease

Drug Discovery - Second Edition eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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