Parkinson's Research News

April 19, 2024

Top Headlines

AI Speeds Up Drug Design for Parkinson's by Ten-Fold

Apr. 17, 2024 — Researchers have used artificial intelligence techniques to massively accelerate the search for Parkinson's disease treatments. The researchers designed and used an AI-based strategy to identify compounds that block the clumping, or aggregation, of ...

Scientists Identify Cell Vulnerability 'Fingerprint' Related to Parkinson's, Lewy Body Dementia

Apr. 16, 2024 — A new study offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some dementias. The ...

Parkinson's Disease: New Theory on the Disease's Origins and Spread

Apr. 11, 2024 — New hypothesis paper builds on a growing scientific consensus that Parkinson's disease route to the brain starts in either the nose or the gut and proposes that environmental toxicants are the likely ...

Common Degenerative Brain Disease May Begin to Develop in Middle Age

Mar. 26, 2024 — Lewy body disease may be more common in middle-aged people than previously thought, according to a recent study. In the study, almost one in ten of over 50-year-olds were found to have tissue markers of Lewy body disease in the ...

Latest Headlines

updated 10:43pm EDT

Protecting Brain Cells With Cannabinol

Apr. 17, 2024 — Scientists created four cannabis-derived CBN analogs (chemical look-a-likes) with enhanced neuroprotective properties and potential for therapeutic application in neurological disorders like ...

Researchers Use Deep Brain Stimulation to Map Therapeutic Targets for Four Brain Disorders

Feb. 22, 2024 — A new study demonstrated the use of deep brain stimulation (DBS) to map a 'human dysfunctome' -- a collection of dysfunctional brain circuits ...

Study Finds Pesticide Use Linked to Parkinson's in Rocky Mountain, Great Plains Region

Feb. 28, 2024 — Pesticides and herbicides used in farming have been linked to Parkinson's disease in the Rocky Mountain and Great Plains region of the country, ...

Newly Discovered Brain Cells Play a Key Role in Right and Left Turns

Feb. 12, 2024 — Researchers have discovered a network of neurons in the brain of mice that help them make right and left turns. In the future, the discovery may be used in treatment for Parkinson's ...

Protein Modifications Key Influencers in Neurodegenerative Diseases

Feb. 12, 2024 — Exploring the post-translational modifications of a key protein in Parkinson's disease, researchers uncover potential pathways for future therapies in neurodegenerative diseases in ...

Researchers 3D-Print Functional Human Brain Tissue

Feb. 1, 2024 — It's an achievement with important implications for scientists studying the brain and working on treatments for a broad range of neurological and neurodevelopmental disorders, such as Alzheimer's and ...

A Neurological Disease Paradigm Shift

Jan. 23, 2024 — Scientists argue that Parkinson's disease complexity demands a new way of classifying the disease for research purposes, one based not on clinical diagnosis but biology. The authors have called their ...

Using Magnetized Neurons to Treat Parkinson's Disease Symptoms

Jan. 18, 2024 — Electrical deep brain stimulation (DBS) is a well-established method for treating disordered movement in Parkinson's disease. However, implanting electrodes in a person's brain is an invasive and ...

Engineering a More Elegant Deep Brain Stimulation Therapy for Parkinson's

Jan. 18, 2024 — A team of physicians, neuroscientists and engineers demonstrated two new strategies that use deep brain stimulation to improve the symptoms of Parkinson's disease. By simultaneously targeting two key ...

SARS-CoV-2 Can Infect Dopamine Neurons Causing Senescence

Jan. 17, 2024 — A new study reported that SARS-CoV-2, the virus that causes COVID, can infect dopamine neurons in the brain and trigger senescence -- when a cell loses the ability to grow and divide. The researchers ...

Even Cells Know the Importance of Recycling

Mar. 14, 2024 — Researchers uncovered the mechanistic details behind how several proteins interact to help cells recognize and remove damaged mitochondria. Optineurin (OPTN) and its interactions are needed to ...

A Common Marker of Neurological Diseases May Play Role in Healthy Brains

Jan. 9, 2024 — Researchers have discovered that a protein called phosphorylated -synuclein, which is associated with several neurodegenerative diseases such as Parkinson's disease and Lewy body dementia, is ...

Inspired by Greek Mythology, This Potential Drug Shows Promise for Vanquishing Parkinson's RNA in Early Studies

Jan. 9, 2024 — A new discovery takes its inspiration from Greek mythology. The compound is described as a chimera, because it battles a toxic cause of Parkinson's in two ...

Soft Robotic, Wearable Device Improves Walking for Individual With Parkinson's Disease

Jan. 5, 2024 — Researchers have used a soft, wearable robot to help a person living with Parkinson's walk without freezing. The robotic garment, worn around the hips and thighs, gives a gentle push to the hips ...

Newly Discovered Genetic Mutation Protects Against Parkinson's Disease and Offers Hope for New Therapies

Jan. 2, 2024 — A previously unidentified genetic mutation in a small protein provides significant protection against Parkinson's disease and offers a new direction for exploring potential treatments, according ...

Protein Study Could One Day Advance Parkinson's, Breast Cancer Care

Dec. 12, 2023 — New research could one day lead to therapies that prevent or treat diseases and infections tied to a protein that's found in all human cells. A study describes how the protein ubiquitin is ...

Unlocking the Secrets of the Brain's Dopaminergic System

Dec. 5, 2023 — A new organoid model of the dopaminergic system sheds lights on its intricate functionality and potential implications for Parkinson's disease. The model replicates the dopaminergic ...

Revolutionizing the Treatment of Parkinson's Patients

Dec. 5, 2023 — The future treatment of Parkinson's Disease has undergone tremendous development in recent years. Now, a breakthrough in research has emerged, delivering the strongest results for both ...

Coffee Grounds May Hold Key to Preventing Neurodegenerative Diseases

Nov. 21, 2023 — A team of researchers found that caffeic-acid based Carbon Quantum Dots (CACQDs), which can be derived from spent coffee grounds, have the potential to protect brain cells from the damage caused by ...

Nanoplastics Promote Conditions for Parkinson's Across Various Lab Models

Nov. 17, 2023 — Nanoplastics interact with a particular protein that is naturally found in the brain, creating changes linked to Parkinson's disease and some types of ...

Alzheimer's and Parkinson's: Scientists Produce Human Norepinephrine Neurons from Stem Cells

Nov. 17, 2023 — Researchers have identified a protein key to the development of a type of brain cell believed to play a role in disorders like Alzheimer's and Parkinson's diseases and used the discovery to ...

Unravelling the Secrets of Neurodegenerative Diseases, One Protein at a Time

Nov. 17, 2023 — Proteins misfolding and clumping together, a process known as aggregation, is a key feature seen in several neurological conditions, including Alzheimer's and Parkinson's diseases. These ...

Location of Strong Sense of Discomfort in Brain Found

Nov. 6, 2023 — Researchers have identified a new neural circuit in the brain which produces a strong sense of discomfort when activated. The discovery also allows them to show for the first time that the ...

High Biological Age May Increase the Risk of Dementia and Stroke

Nov. 6, 2023 — People who have a higher biological age than their actual chronological age have a significantly increased risk of stroke and dementia, especially vascular ...

Molecular Age of the Eye Determined

Oct. 19, 2023 — A team of researchers have mapped almost 6,000 proteins from different cell types within the eye by analyzing tiny drops of eye fluid that are routinely removed during surgery. The researchers used ...

Researchers Find a Cause of Parkinson's Disease

Oct. 2, 2023 — A significant breakthrough sheds light on the underlying mechanisms of Parkinson's disease, offering the potential for innovative treatments in the ...

A Deep Look Into the Progression of Parkinson's Disease

Sep. 29, 2023 — Scientists have used cutting-edge imaging techniques to shed light on the progression of Parkinson's disease by studying how the main culprit, the protein alpha-synuclein, disrupts cellular ...

Parkinson's: Are Our Neurons More Vulnerable at Night?

Sep. 28, 2023 — Disturbances in sleep patterns and the internal biological clock are frequently associated with Parkinson's disease. However, the link between biological rhythm and neuronal degeneration remains ...

Compensation by Healthy Brain Parts Alleviates Parkinson Symptoms

Sep. 28, 2023 — In Parkinson's disease, the cerebral cortex can take over tasks from a deeper part of the brain that has been damaged, where cells that make dopamine have been lost. The strength of compensation ...

New Blood Marker Can Identify Parkinsonian Diseases

Sep. 18, 2023 — Is it possible that a single biomarker can detect all types of diseases related to dopamine deficiency in the brain? Yes, that's what a research group is discovering. 'We have observed that ...