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$4.8 million grant supports research on TDP-43 misfolding in neurodegenerative diseases

A new $4.8 million grant will support researchers from Indiana University School of Medicine and the Medical Research Council Laboratory of Molecular Biology to study how human neurodegenerative diseases are affected by the misfolding of the protein TDP-43.

23 Apr 2024

Scientists map all yeast proteins across cell cycle for the first time

An international team led by researchers at the University of Toronto has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the cell cycle, which required a combination of deep learning and high-throughput microscopy.

23 Apr 2024

Study explores the effects of ovulation inducing method on embryo quality

Low birth rates have become a serious problem in many developed countries throughout the world, with Japan being a prime example. In Japan particularly, aging and stress have led to a massive rise in infertility, which now affects one in every 4.4 couples.

22 Apr 2024

New vaccine promises broad protection against SARS-CoV-2 and other sarbecoviruses

Researchers at Georgia Tech and the University of Wisconsin have created a broad-spectrum vaccine capable of defending against various SARS-CoV-2 variants and related bat coronaviruses.

17 Apr 2024

Novel antibacterial discovery: Umbrella toxin particles secreted by Streptomyces

Researchers have discovered toxic protein particles, shaped like umbrellas, that soil bacteria known as Streptomyces secrete to squelch competitors, especially others of their own species.

17 Apr 2024

Study reveals structural dynamics of key hearing receptor

Professor Yunje Cho's research team from the Department of Life Sciences at Pohang University of Science and Technology (POSTECH, Republic of Korea) has collaborated with Professor Kwang Pyo Kim's group from the Department of Applied Chemistry at Kyung Hee University (KHU, ROK), Professor Vsevolod Katritch's team from the University of Southern California (USC, USA), and Professor Carol V. Robinson from the University of Oxford (UK) to uncover the mysteries surrounding a specific receptor protein associated with hearing.

15 Apr 2024

Texas A&M scientists elucidate how phages disarm antibiotic-resistant bacteria

Bacterial infections pose significant challenges to agriculture and medicine, especially as cases of antibiotic-resistant bacteria continue to rise.

15 Apr 2024

Visualizing centriole genesis with microscopy and kinematic reconstruction techniques

Cells contain various specialized structures - such as the nucleus, mitochondria or peroxisomes - known as "organelles''.

12 Apr 2024

Novel signaling pathway identified in lysosome damage response

Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm.

8 Apr 2024

Concordia researchers link vaping additives to lung damage

The health risks associated with consumption of tobacco and cannabis products are well-established by now. Much less understood are the risks associated with vaping, particularly flavoured products popular with young adults.

4 Apr 2024

Innovative approach to disrupt misfolding of tau proteins in neurodegenerative diseases

A spectrum of neurodegenerative diseases, including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are due to the accumulation of abnormal, misfolded tau proteins in the brain.

3 Apr 2024

Novel antibiotic-infused hydrogel kills bacteria and promotes cell growth

Hydrogels are popular for use in skin ailments and tissue engineering. These polymer-based biocompatible materials are useful for their abilities to retain water, deliver drugs into wounds, and biodegrade.

2 Apr 2024

Rare variants in the YKT6 gene cause new neurological disorder, study finds

A recent collaborative study has discovered rare variants in the YKT6 gene as the cause of a new neurological disorder characterized by developmental delays along with severe progressive liver disease and a potential risk for liver cancer.

1 Apr 2024

Unlocking clotting mechanisms in caterpillar hemolymph for medical use

Blood is a remarkable material: it must remain fluid inside blood vessels, yet clot as quickly as possible outside them, to stop bleeding. The chemical cascade that makes this possible is well understood for vertebrate blood.

30 Mar 2024

New insights into gas vesicle clustering in bacteria open doors for biomedical applications

Gas vesicles are hollow structures made of protein found in the cells of certain microorganisms, and researchers at Rice University believe they can be programmed for use in biomedical applications.

29 Mar 2024

Study reveals protein structure similarities in Alzheimer's and Down syndrome

More than 90% of people with Down syndrome, the most common chromosomal disorder in humans and the most frequent genetic cause of intellectual disability, are diagnosed with Alzheimer's disease by ages 55-60.

29 Mar 2024

Experts advocate three-pronged approach to identifying missing tuberculosis cases

In the journey towards a world free of Tuberculosis (TB), the crucial first step begins with identifying individuals affected by the disease.

25 Mar 2024

Researchers shed light on proteins controlling the development of ovaries in mice

Researchers at the Francis Crick Institute have shed light on the proteins controlling the development of ovaries in mice before and after birth.

22 Mar 2024

Semarion introduces SemaCyte Multiplexing Platform to enhance cell assay data quality and speed during drug discovery

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From Semarion 20 Mar 2024

Nano-sized toxic metals found in cannabis vaping liquids even before the first use

Vapes have often been heralded as a "safer" way to consume either nicotine or cannabis, where legal to do so.

19 Mar 2024