Simultaneous measurement of multiple analytes in high-throughput assays requires the design of integrated sensory elements. The latest development in this field is an engineering masterpiece based on microfluidics, photolithography and polymer science.
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References
Pregibon, D.C., Toner, M. & Doyle, P.S. Science 315, 1393–1396 (2007).
Fenniri, H. Combinatorial Chemistry: a Practical Approach (Oxford University Press, Oxford, 2000).
Fenniri, H., Chun, S., Ding, L., Zyrianov, Y. & Hallenga, K. J. Am. Chem. Soc. 125, 10546–10560 (2003).
Fodor, S.P.A. et al. Nature 364, 555–556 (1993).
MacBeath, G. & Schreiber, S.L. Science 289, 1760–1763 (2000).
Nolan, J.P. & Sklar, L.A. Trends Biotechnol. 20, 9–12 (2002).
Fan, J.B., Chee, M.S. & Gunderson, K.L. Nat. Rev. Genet. 7, 632–644 (2006).
Fodor, S.P.A. et al. Science 251, 767–773 (1991).
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Fenniri, H., Alvarez-Puebla, R. High-throughput screening flows along. Nat Chem Biol 3, 247–249 (2007). https://doi.org/10.1038/nchembio0507-247
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DOI: https://doi.org/10.1038/nchembio0507-247
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