Chembiochem : a European journal of chemical biology

(ISSN: 1439-4227, 1439-7633)

Table of Contents

From Chembiochem : a European journal of chemical biology

2023 -

  • Enlighting electron routes in oxyfunctionalizing Synechocystis sp. PCC 6803. 
  • Coenzyme A Thioester Intermediates as Platform Molecules in Cell-Free Chemical Biomanufacturing. 
  • Dimer stabilization by SpyTag/SpyCatcher coupling of the reductase domains of a chimeric P450 BM3 monooxygenase from Bacillus spp. improves its stability, activity and purification. 
  • New dipterocarpol-based molecules with α-glucosidase inhibitory and hypoglycemic activity. 
  • γ-Glutamylation of Isopropylamine by Fermentation. 
  • A Tight Contact: the Expanding Application of Salicylaldehydes in Lysine-targeting Covalent Drugs. 
  • Hoechst-modification on oligodeoxynucleotides for efficient transport to the cell nucleus and gene regulation. 
  • Enzyme-Instructed Host-Guest Assembly/Disassembly for Biomedical Applications. 
  • Quantitative analysis of 2D EXSY NMR spectra of strongly coupled spin systems in transmembrane exchange. 
  • Targeted preparation and NMR spectroscopic characterization of Lys11-linked ubiquitin trimers. 
  • Virtual Screening Assisted Search for Inhibitors of the Translocated Intimin Receptor of Enteropathogenic Escherichia Coli. 
  • Integrated Electrochemical and Optical Biosensing in Organs-on-Chip. 
  • A Lateral Flow Assay Based on Streptavidin-biotin Amplification System with Recombinase Polymerase Amplification for Rapid and Quantitative Detection of Salmonella enteritidis. 
  • Recent Advances in RNA-Targeted Cancer Therapy. 
  • Recent Advances and Challenges in Enzymatic Depolymerization and Recycling of PET Wastes. 
  • An Enzymatic Cofactor Regeneration System for the in-Vitro Reduction of Isolated C=C Bonds by Geranylgeranyl Reductases. 
  • Environmentally Friendly Degradation and Detoxification of Rifampicin by a Bacterial Laccase and Hydrogen Peroxide. 
  • Integrin Facilitates the Internalization of TAT Peptide Conjugated to RGD Motif in Model Lipid Membranes. 
  • Shedding Light on the D1 -Like Receptors: A Fluorescence-Based Toolbox for Visualization of the D1 and D5 Receptors. 
  • Fluorescent Tools for the Imaging of Dopamine D2 -Like Receptors. 
  • Chimeric Small Molecules for Detouring Drugs into Mitochondria to Engender Apoptosis in Cancer Cells. 
  • Fluorimetric Cell Analysis with 9-Aryl-Substituted Berberine Derivatives as DNA-Targeting Fluorescent Probes. 
  • Investigation Of The Biosynthesis Pathway That Generates cis-Jasmone. 
  • CoFeSe2@DMSA@FA nanocatalyst for amplification of oxidative stress to achieve multimodal tumor therapy. 
  • Preferential Binding of a Red Emissive Julolidine Derivative to a Promoter G-quadruplex. 
  • Antibacterial Photodynamic Therapy by Zn(II)-Curcumin Complex: Synthesis, Characterization, DFT Calculation, Antibacterial Activity, and Molecular Docking. 
  • Increasing the Stability of Flavin-Dependent Halogenases by Disulfide Engineering. 
  • Bacterial Isothiocyanate Biosynthesis by Rhodanese-Catalyzed Sulfur Transfer onto Isonitriles. 
  • Chemoenzymatic Synthesis of a New Germacrene Derivative Named Germacrene F. 
  • Biosynthesis of Octacosamicin A: Uncommon Starter/extender Units and Product Releasing via Intermolecular Amidation. 
  • Inhibition of Aurora-A/N-Myc protein-protein interaction using peptidomimetics: Understanding the role of peptide cyclization. 
  • Discovery of 14-3-3 PPI Stabilizers by Extension of an Amidine-Substituted Thiophene Fragment. 
  • Lipid Droplets Specific Fluorophore for Demarcation of Normal and Diseased Tissues. 
  • pH-Responsive Trihydroxylated Piperidines Rescue The Glucocerebrosidase Activity in Human Fibroblasts Bearing The Neuronopathic Gaucher-Related L444P/L444P Mutations in GBA1 Gene. 
  • Application of Vitreoscilla Hemoglobin as a Green and Efficient Biocatalyst for the Synthesis of Benzoxazoles in Water. 
  • Drug Encapsulation via Peptide-Based Polyelectrolyte Complexes. 
  • Unlocking The Mysteries of DNA Adducts with Artificial Intelligence. 
  • Immunological Quantitation of the Glycation Site Lysine-414 in Serum Albumin in Human Plasma Samples by Indirect ELISA Using Highly Specific Monoclonal Antibodies. 
  • ThermoBRET: A Ligand-Engagement Nanoscale Thermostability Assay Applied to GPCRs. 
  • Cleaving Folded RNA with DNAzyme Agents. 
  • Inducin Triggers LC3-Lipidation and ESCRT-Mediated Lysosomal Membrane Repair. 
  • Light-driven Metabolic Pathways in Non-photosynthetic Biohybrid Bacteria. 
  • Orthogonal End Labelling of Oligonucleotides through Dual Incorporation of Click-Reactive NTP Analogues. 
  • Dissection of MKK6 and p38 Signaling Using Light-Activated Protein Kinases. 
  • Catcher/Tag Toolbox: Biomolecular Click-Reactions For Protein Engineering Beyond Genetics. 
  • Prodrug-Type Phosphotriester Oligonucleotides with Linear Disulfide Promoieties Responsive to Reducing Environment. 
  • Development of Ruthenium Nanophotocages with Red or Near-Infrared Light-Responsiveness. 
  • Interrogating Aptamer Chemical Space Through Modified Nucleotide Substitution Facilitated by Enzymatic DNA Synthesis. 
  • Harnessing a Biocatalyst to Bioremediate the Purification of Alkylglycosides. 
  • Thiol-Disulfide Exchange Kinetics and Redox Potential of the Coenzyme M and Coenzyme B Heterodisulfide, an Electron Acceptor Coupled to Energy Conservation in Methanogenic Archaea. 
  • High-Content Image-Based Screening and Deep Learning for the Detection of Anti-Inflammatory Drug Leads. 
  • Analytical Tools for Dynamic Combinatorial Libraries of Cyclic Peptides. 
  • Discovery of NSD2-Degraders from Novel and Selective DEL Hits. 
  • Analysing Megasynthetase Mutants at High Throughput Using Droplet Microfluidics. 
  • Interfacing Whole Cell Biocatalysis with a Biocompatible Pictet-Spengler Reaction for One-Pot Syntheses of Tetrahydroisoquinolines and Tryptolines. 
  • From Natural Insulin to Designed Analogs: A Chemical Biology Exploration. 
  • Impact of Metabolic Stress on BeWo Syncytiotrophoblast Function. 
  • Bioorthogonal Chemistry in Translational Research: Advances and Opportunities. 
  • Efficient Oxidation of 5-Hydroxymethylfurfural Using a Flavoprotein Oxidase from the Honeybee Apis mellifera. 
  • Structural Analyses of DP-1, a Protein with the Ability To Bind Gold Nanoparticles, by Using Nuclear Magnetic Resonance Spectroscopy. 
  • Selection of Highly Specific DNA Aptamer for the Development of QCM-Based Arsenic Sensor. 
  • Creating NADP+ -Specific Formate Dehydrogenases from Komagataella phaffii by Enzymatic Engineering. 
  • Overcoming Biochemical Limitations of Galactose Oxidase through the Design of a Solid-Supported Self-Sufficient Biocatalyst. 
  • Effect of Hyaluronic Acid on the Self-Assembly of a Dipeptide-Based Supramolecular Gel. 
  • Stereoselective Biocatalytic α-Deuteration of L-Amino Acids by a Pyridoxal 5'-Phosphate-Dependent Mannich Cyclase. 
  • Small Molecules Targeting Human UDP-GlcNAc 2-Epimerase. 
  • Covalent Targeting of Glutamate Cysteine Ligase to Inhibit Glutathione Synthesis. 
  • Towards Copper(I) Clusters for Photo-Induced Oxidation of Biological Thiols in Living Cells. 
  • Double Stranded DNA Binding Stapled Peptides: An Emerging Tool for Transcriptional Regulation. 
  • Biotransformation of Polyunsaturated Fatty Acids to Trioxilins by Lipoxygenase from Pleurotus sajor-caju. 
  • A Case of Convergent Evolution: The Bacterial Sesquiterpene Synthase for 1-epi-Cubenol from Nonomuraea coxensis. 
  • Cross-Binding of Adenosine by Aptamers Selected Using Theophylline. 
  • Prebiotic Synthesis of 3',5'-Cyclic Adenosine and Guanosine Monophosphates through Carbodiimide-Assisted Cyclization. 
  • Exploring the Substrate Switch Motif of Aromatic Ammonia Lyases. 
  • Formation and Effects of Upstream DNA-RNA Base Pairing in Telomerase. 
  • Biotransformation Of l-Tryptophan To Produce Arcyriaflavin A With Pseudomonas putida KT2440. 
  • Development of Multivalent Conjugates with a Single Non-Canonical Amino Acid. 
  • Biotransamination of Furan-Based Aldehydes with Isopropylamine: Enzyme Screening and pH Influence. 
  • Recent Advances in Chemical Synthesis of Structural Domains of Lipopolysaccharides from the Commensal Gut-Associated Microbiota. 
  • Improving the Enantioselectivity of CHMOBrevi1 for Asymmetric Synthesis of Podophyllotoxin Precursor. 
  • Phenolic Substitution in Fidaxomicin: A Semisynthetic Approach to Antibiotic Activity Across Species. 
  • The Conversion of UDP-Glc to UDP-Man: In Silico and Biochemical Exploration To Improve the Catalytic Efficiency of CDP-Tyvelose C2-Epimerases. 
  • Ligand-Directed Chemistry on Glycoside Hydrolases - A Proof of Concept Study. 
  • Bispidine as a Versatile Scaffold: From Topological Hosts to Transmembrane Transporters. 
  • A Degron Blocking Strategy Towards Improved CRL4CRBN Recruiting PROTAC Selectivity. 
 
 

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