Thyroid Disease Resource Center Features

• Alert FDA Approves Novel 'Tissue Agnostic' Cancer Drug Larotrectinib targets a key genetic driver that occurs in multiple types of cancer, rather than a specific tumor type.
  FDA Approvals, November 27, 2018
• An Unsuspected Complication With Immune Checkpoint Blockade This rare occurrence of immune-related hyperthyroidism emphasizes the importance of the differential diagnosis when dealing with patients on immune checkpoint inhibitors.
  Journal of Medical Case Reports, November 21, 2018
• Critical Isotope for Thyroid Cancer Now Produced in the US For the first time in 30 years, iodine-131, a critical radioisotope used for diagnosing and treating thyroid cancer and hyperthyroidism, is being produced in the US.
  Medscape Medical News, November 20, 2018
• The Baby With a Swollen Eyelid An 8-month-old girl's eye swelling appears to be getting worse when she presents at your clinic. Can you diagnose the problem?
  Medscape Ophthalmology, November 19, 2018
• Medical Treatment of Fibroids With Heavy Menstrual Bleeding Dr Peter Kovacs comments on a review that offers insights into the indications and mechanism of action of ulipristal acetate.
  Medscape Ob/Gyn, November 19, 2018
• PCOS 2018 Immunotherapy Adverse Events More Common Than Initially Reported The rate of immunotherapy adverse events, as evidenced in real world data, is much higher than was previously reported in the pivotal clinical trials of these agents.
  Medscape Medical News, November 19, 2018
• Targeted Therapy to Resensitize Tumors to Radioactive Iodine How might targeted therapy help patients with advanced thyroid cancer that has become radioactive iodine refractory?
  Journal of Clinical Endocrinology & Metabolism, November 19, 2018
• AHA 2018 Overtreating Hypothyroidism: Link to Atrial Fibrillation The new findings from more than 170,000 patients are consistent with previous smaller studies, suggesting the possible need to re-think free T4 in hypothyroidism treatment.
  Medscape Medical News, November 12, 2018
• The Relation Between Thyroid Function and Anemia Is there a greater risk for developing anemia among patients with thyroid disease?
  Journal of Clinical Endocrinology & Metabolism, November 12, 2018
• ThyroSeq Test Helps Avoid Unnecessary Thyroid Surgeries The multigene molecular classifier ThyroSeq shows high sensitivity, specificity, and detailed genetic profiles, allowing fewer unnecessary diagnostic surgeries for indeterminate thyroid nodules.
  Medscape Medical News, November 09, 2018
• NCRI 2019 Trial Confirms Low-Dose Radiation for Low-Risk Thyroid Cancer The safety and efficacy of low-dose radioactive iodine in patients with low-risk thyroid cancer has been confirmed by UK researchers in the longest-running trial of radiation treatment in this setting.
  Medscape Medical News, November 08, 2018
• Debate Continues Over Universal Thyroid Screening in Pregnancy Majority of thyroid dysfunction cases seen in pregnancy consist of subclinical disease for which screening and treatment remain controversial.
  Medscape Medical News, November 06, 2018
• ThyroSeq V2.0 Molecular Testing for Thyroid Nodules A new study examines the cost-effectiveness of a novel molecular test for indeterminate thyroid nodules. How does it compare with diagnostic thyroidectomy?
  Endocrine Practice, November 06, 2018
• PD-1 Inhibitor Immune-Related Adverse Events What do we currently know about the immune-related side effects of treatment with PD-1 inhibitors in patients with a preexisting autoimmune disease?
  Journal of Clinical Endocrinology & Metabolism, November 05, 2018
• Could It Be the Sugar?   A 'battle royale' is brewing in the nutrition science field.
  Medscape Internal Medicine, November 01, 2018
• The Love-Hate Relationship With Levothyroxine Levothyroxine, despite being the most prescribed drug in the United States, has many patients disenchanted and looking to T3 for symptom relief. How should clinicians approach the T4/T3 controversy?
  American Thyroid Association, October 25, 2018
• Benign Follicular Thyroid Lesion and Rising Thyroglobulin The misdiagnosis of follicular thyroid lesions as benign can have devastating consequences. How are these difficult cases best diagnosed?
  Endocrine Practice, October 23, 2018
• ATA 2018 Thermal Ablation Approaches Similar in Efficacy for Benign Nodules Comparison of radiofrequency ablation, laser ablation, and high-intensity focused ultrasound showed the three approaches had similar efficacy for the treatment of benign thyroid nodules.
  Medscape Medical News, October 18, 2018
• ATA 2018 Selumetinib: No Benefit Boosting RAI for High Risk Thyroid Cancer Though previous research showed the MEK1/2 inhibitor could improve RAI effect, the phase 3 trial failed to reach its primary endpoint.
  Medscape Medical News, October 16, 2018
• ATA 2018 New RET Inhibitors Show Reduced Toxicities in Thyroid Cancer The precision-targeted therapies show early, encouraging signs of reduced toxicities for medullary, thyroid cancers.
  Medscape Medical News, October 15, 2018