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Researchers identify a ‘gene module’ involved in both depression and cardiovascular disease

Depression and cardiovascular disease (CVD) are serious concerns for public health. Approximately 280 million people worldwide have depression, while 620 million people have CVD. It has been known since the 1990s that the two diseases are somehow related.

25 Apr 2024

New system personalizes chemotherapy doses for cancer patients

When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient's body surface area. This is estimated by plugging the patient's height and weight into an equation, dating to 1916, that was formulated from data on just nine patients.

24 Apr 2024

Study links acid-reducing drugs to increased risk of migraine

People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a study published in the April 24, 2024, online issue of Neurology Clinical Practice, an official journal of the American Academy of Neurology.

24 Apr 2024

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

Under the leadership of PD Dr. Niklas Klümper, Assistant Physician at the Department of Urology at the University Hospital Bonn (UKB) and Clinician Scientist of the BMBF-funded ACCENT program and PD Dr. Markus Eckstein, senior physician at the Institute of Pathology at the Uniklinikum Erlangen of the Friedrich-Alexander-University Erlangen-Nürnberg (FAU), an interdisciplinary research team has published new findings that indicate which patients with advanced urothelial carcinoma could benefit in particular from the new targeted therapy with the antibody-drug conjugate enfortumab vedotin.

24 Apr 2024

Anesthetic midazolam boosts survival after cardiac arrest

If a patient is successfully resuscitated after a cardiac arrest and circulation resumes, they are not out of the woods yet.

24 Apr 2024

Younger adults with atrial fibrillation face higher rates of heart failure and stroke

The risk factor (RF) burden, clinical outcomes, and long-term survival among patients with atrial fibrillation (AF) under 65 years of age.

24 Apr 2024

Research highlights best window for paxlovid administration in COVID-19 patients

Researchers have described the optimal timing for COVID-19 patients to take the antiviral, Paxlovid, to get the most benefit from the treatment, according to a study published April 16 in eLife.

23 Apr 2024

U-M scientists develop new tool to better understand neuronal signaling

University of Michigan researchers have developed a new tool to better understand how chemicals like dopamine and epinephrine interact with neurons.

23 Apr 2024

State-of-the art imaging reveals how lipid metabolism is changed in Alzheimer's disease

Alzheimer's disease causes significant problems with memory, thinking and behavior and is the most common form of dementia, affecting more than 50 million people around the world each year.

23 Apr 2024

Analysis finds significant variations in national COVID-19 treatment recommendations

National clinical guidelines for the treatment of COVID-19 vary significantly around the world, with under-resourced countries the most likely to diverge from gold standard (World Health Organization; WHO) treatment recommendations, finds a comparative analysis published in the open access journal BMJ Global Health.

23 Apr 2024

Investigating the efficacy and safety of existing drugs in patients with rare immune diseases

This month the first study within the DRIMID consortium (DRIMID stands for Drug Rediscovery for Rare Immune Mediated Inflammatory Diseases) has started.

23 Apr 2024

Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

Tafenoquine, a prodrug that could fulfill the criteria for a mass eradication campaign.

23 Apr 2024

CN Bio raises $21 million USD in first close of Series B investment round

Bayland Capital and founding shareholder, CN Innovations Holdings Ltd, to invest $10 M and $5.5 M, respectively. Investment will expand product development and scaling of the organization to meet increased demand for Organ-on-a-Chip (OOC) solutions.

23 Apr 2024

California legislators debate froot loops and free condoms

California state lawmakers this year are continuing their progressive tilt on health policy with dozens of proposals including a ban on a Froot Loops ingredient and free condoms for high schoolers.

23 Apr 2024

New technique tracks drug use through smartphones

A simple and convenient method to collect drug use data from the surface of a smartphone is revealed for the first time in a new study published in De Gruyter's Clinical Chemistry and Laboratory Medicine. By helping clinicians understand what drugs people are taking in certain contexts, the research could protect public health and improve the treatment of patients suspected of overdosing.

23 Apr 2024

Research explores how moms' obesity reprograms babies

Research increasingly suggests that when a woman with obesity becomes pregnant, a process of "fetal reprogramming" increases the risk that her baby will face problems like obesity, Type 2 diabetes and liver disease earlier in life.

23 Apr 2024

New tool hunts for Alzheimer's clues in gut microbiome

Cleveland Clinic researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease.

23 Apr 2024

The vital role of therapeutic alliances in psychedelic treatment

Drug effects have dominated the national conversation about psychedelics for medical treatment, but a new study suggests that when it comes to reducing depression with psychedelic-assisted therapy, what matters most is a strong relationship between the therapist and study participant.

23 Apr 2024

Risks of antipsychotic use in dementia extend beyond previous alerts, study shows

Antipsychotic use in people with dementia is associated with higher risks of a wide range of serious health outcomes compared with non-use, according to a new study from a collaboration across the Universities of Manchester, Nottingham, Edinburgh and Dundee.

23 Apr 2024

Study shows meth users have lower empathy and higher aggression, ecstasy users show normal empathy but more impulsive aggression

A study in the European Neuropsychopharmacology journal finds that methamphetamine users show lower empathy and higher aggression, whereas ecstasy (MDMA) users exhibit increased impulsive aggression but normal empathy levels.

23 Apr 2024

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Drugs News and Research

Researchers identify a ‘gene module’ involved in both depression and cardiovascular disease

New system personalizes chemotherapy doses for cancer patients

Study links acid-reducing drugs to increased risk of migraine

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

Anesthetic midazolam boosts survival after cardiac arrest

Younger adults with atrial fibrillation face higher rates of heart failure and stroke

Research highlights best window for paxlovid administration in COVID-19 patients

U-M scientists develop new tool to better understand neuronal signaling

State-of-the art imaging reveals how lipid metabolism is changed in Alzheimer's disease

Analysis finds significant variations in national COVID-19 treatment recommendations

Investigating the efficacy and safety of existing drugs in patients with rare immune diseases

Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

CN Bio raises $21 million USD in first close of Series B investment round

California legislators debate froot loops and free condoms

New technique tracks drug use through smartphones

Research explores how moms' obesity reprograms babies

New tool hunts for Alzheimer's clues in gut microbiome

The vital role of therapeutic alliances in psychedelic treatment

Risks of antipsychotic use in dementia extend beyond previous alerts, study shows

Study shows meth users have lower empathy and higher aggression, ecstasy users show normal empathy but more impulsive aggression

Drug Discovery - Second Edition eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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