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San Antonio Spurs at Los Angeles Lakers odds, picks and best bets

The Los Angeles Lakers (37-11) host the San Antonio Spurs (22-27) Tuesday at Staples Center for a 10 p.m. ET tip-off. We analyze the Spurs-Lakers sports betting odds and lines, with NBA betting advice and tips around the matchup.

Spurs at Lakers: Key Injuries

Lakers

  • PG Alex Caruso (neck) probable
  • DeMarcus Cousins (knee) out
  • PF Anthony Davis (shoulder) probable

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Spurs at Lakers: Odds, lines, picks and betting tips

NBA odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 10:45 a.m. ET.

Prediction

Lakers 128, Spurs 120

Moneyline (ML)

The Lakers (-769) are an easy choice once again on home court, if not for the cost-prohibitive odds. The top seed in the Western Conference is 16-6 at home this season and 6-4 over its last 10 games overall. The Spurs (+525) are 5-5 over their last 10 games, but just 8-15 on the road while entering Tuesday in 10th place in the West. They lost 108-105 to the Los Angeles Clippers Monday as they suit up for the second night in a row.

The Lakers lead the head-to-head season series 2-0 with 103-96 and 114-104 victories both coming in San Antonio. We’ll PASS on the moneyline bet as they go for the season sweep due to the heavy chalk. A $10 bet on the Lakers to win straight up will return a profit of just $1.30.

Line/Against the Spread (ATS)

Back the SPURS (+12.5, -115) as they’re catching double-digit points on the road and will need only to stay within 12 points in a loss. The Lakers’ previous two head-to-head victories came by margins of 10 and 7 points. San Antonio is 22-26-1 against the spread overall and a strong 13-9 on the road. Los Angeles is 25-22-1 ATS overall and an unimpressive 11-10-1 at home.

The Spurs have lost by 10 or more points just seven times this season and not since Jan. 10. They’re 4-1 ATS on the second half of back-to-backs.

Over/Under (O/U)

The Spurs are also 4-1 against the Over/Under when playing on no rest. As such, we’ll back the OVER 229.5 (-106). The two teams combine to average 227.4 points per game this season with 220.7 PPG allowed. The tired Spurs will struggle on defense against LeBron James and Co., but they’ll close the gap enough late to send this one Over the projected total.

Esten’s NBA betting record: 178-145

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