The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is establishing nine new Collaborative Research Centres (CRC) to promote world-class research at universities. This was announced by the relevant Grants Committee, which met by video conference. The new CRCs will initially receive a total of approximately €111 million over a period of four years from 1 July 2022 onwards. This includes a 22-percent programme allowance for indirect project-related costs. Two of the new consortia are CRC/Transregios (TRR) and are distributed across multiple applicant universities.
In addition to the nine new institutions, the Grants Committee agreed to an additional funding period for another 19 CRCs, including six CRC/Transregios. Collaborative Research Centres allow researchers to tackle innovative, challenging and long-term research projects within the network and should enable institutional priority area development and structural development at the applicant universities. CRCs are awarded funding for a maximum of twelve years. From July 2022 onwards there will be a total of 276 CRCs receiving DFG funding.
The new Collaborative Research Centres in detail
(in alphabetical order of host university, with information on the spokesperson as well as the other applicant universities):
In recent years, computer processing capacity has grown increasingly. Yet computing capacity alone is not enough to adequately cope with the current flood of data and the complexity of models that describe scientific and technical phenomena. Even established methods of signal processing, machine learning and the numerical solution of partial differential equations are reaching their limits. For this reason, structures hidden in the data need to be analysed and understood in order to be able to work with better adapted methods in the future. Specifically, algorithms are to be developed that identify simple substructures (sparsity) contained in high-dimension data and that use these to solve otherwise unsolvable problems. The Collaborative Research Centre Sparsity and Singular Structures seeks to apply these algorithms in particular to models that are singular in certain areas, i.e. that do not reliably describe physical reality everywhere due to their underlying principles. (RWTH Aachen, spokesperson: Professor Dr. Holger Rauhut)
Understanding virtuality no longer as the exception but as the norm – this is the starting point for the research work to be done by the Collaborative Research Centre Virtual Living Environments. Consideration will be given to a range of different aspects such as infrastructures, emotions and physicality, knowledge, spatiality, sociality and interaction. Which social subsystems implement virtuality and how? And what consequences does this have for individual subjects and their constitution, for material and aesthetic practices, and for social organisations and operations? Researchers in the fields of media studies, philology and literary studies as well as education, history, art history, social psychology and social anthropology will seek to answer these questions together. (University of Bochum, spokesperson: Professor Dr. Stefan Rieger)
The stroma-vascular compartment (or stromal vascular fraction – SVF) is an essential component of every organ. It is composed of blood and lymph vessels as well as fibroblasts, among other things, and forms the structure in which immune cells from the blood enter the damaged tissue after organ damage. The aim of the Collaborative Research Centre Damage Control by the Stroma-Vascular Compartment is to understand the contribution made by different SVF cell populations in tissue repair in the heart, brain and blood vessels. The focus is particularly on the analysis of the mechanisms and the molecular players that orchestrate the response to injury in a multicellular context. This approach aims to shed light on mechanisms that can be used in the future to optimise the SVF response to damage, improve tissue recovery and thereby increase resilience to damage. (University of Frankfurt/Main, spokesperson: Professor Dr. Ralf P. Brandes)
Dynamic protein assemblies and molecular machines in cell membranes are essential to vital life processes. They keep the functionally different spaces within a cell in balance, convert energy, shift nutrients and metabolites, control communication within and between cells and mediate interactions with pathogens. Yet they are particularly difficult to research, so despite the vital role they play, little is known about them. The overarching goal of the Collaborative Research Centre Protein Assemblies and Machinery in Cell Membranes is to elucidate the organisational principles and functional mechanisms involved, with the aim of laying the basis for a deeper analysis of cellular processes. (University of Frankfurt/Main, spokesperson: Professor Dr. Robert Tampé)
The Collaborative Research Centre Molecular Circuits of Heart Disease addresses questions about the development and progression of different types of heart failure. The researchers involved aim to be able to offer individual, tailor-made treatments for various heart diseases. To this end, they will integrate knowledge of specific causes, signalling pathways and phenotypes by linking experimental and patient data with systems biology and mathematical modelling approaches. By doing so, they hope to decipher the underlying “molecular circuits” of heart disease. (University of Heidelberg, spokesperson: Professor Dr. Johannes Backs)
Magnetic resonance (MR) is the most chemically specific and at the same time most versatile measurement method for gaining detailed information about the structure and function of molecular matter and therefore the fundamental method for carrying out chemical, biological and material science characterisations. Nonetheless, the low sensitivity and relatively high degree of specialisation required for its application stand in the way of widespread use. The Collaborative Research Centre High Performance Compact Magnetic Resonance – HyPERiON aims to challenge conventional concepts along the entire MR signal processing chain in order to improve the sensitivity, resilience and applicability of the method in equal measure. Ultimately, the goal will be to explore new and exciting applications in chemistry and biology, even extending to the field of chemical engineering. (Karlsruhe Institute of Technology, spokesperson: Professor Dr. Jan Gerrit Korvink)
Ecosystems worldwide are threatened by such phenomena as human activity and rapid climate change. Plants are crucial to almost all food webs and therefore to the functioning of ecosystems, so they are forced to adapt to these phenomena. But what is the genetic basis for this? In order to answer this question, the CRC/Transregio Plant Ecological Genetics will investigate the different abilities of selected plant species to adapt to limited resources, abiotic stress and competition with other plants. Field studies and controlled environmental manipulation will be used to clarify whether the functions of genes for adaptation are species-specific or conserved across species. (University of Cologne, spokesperson: Professor Dr. Juliette de Meaux; also applying: University of Düsseldorf)
So-called neutrophil granulocytes are the most abundant circulating white blood cells in human beings and have had mainly antimicrobial functions attributed to them. However, recent findings show that they also have multiple functions in chronic inflammation and tumour development that have not been fully appreciated. The CRC/Transregio Neutrophils: Origin, Fate and Function seeks to understand the role of neutrophils in physiological and pathological immune processes and tap into their potential for therapeutic applications. To this end, investigation will be carried out into how signals in the tissue influence the production and function of neutrophils and how the intracellular processing of signals regulates neutrophil function. In the long term, the aim is to build a bridge to clinical application. (University of Münster, spokesperson: Professor Dr. Oliver Söhnlein; also applying: University of Duisburg-Essen, LMU Munich)
In November 2021, the DFG had already approved funding for the first German-Austrian CRC/Transregio Computational Electric Machine Laboratory: Thermal Modelling, Transient Analysis, Geometry Handling and Robust Design. The decision of the Austrian Science Fund (FWF) was initially pending, but was then made at the beginning of 2022. Since 1 March 2022, the CRC/Transregio has been dedicated to research into a new integrated simulation and design approach for the development of modern electric drives. The aim is to consider all key aspects of a machine from the outset, such as shape and topology, time-dependent operating cycles, complex material behaviour, uncertainties and robustness, new cooling techniques to push thermal limits, noise and vibration, and key performance indicators. (TU Darmstadt, spokesperson: Professor Dr. Sebastian Schöps; also applying: TU Graz, Austria, spokesperson: Professor Dr. Annette Mütze)
The CRCs which will have their funding extended for an additional period
(in alphabetical order of host university, with information on the spokesperson as well as the other applicant universities and with references to the project descriptions in GEPRIS – the DFG internet database for current funding):
CRC Precision Manufacturing by Controlling Melt Dynamics and Solidification in Production Processes (RWTH Aachen, spokesperson: Professor Dr.-Ing. Uwe Reisgen)
https://gepris.dfg.de/gepris/projekt/236616214
CRC In vivo Visualization of Extracellular Matrix Pathology “Matrix in Vision” (Charité – FU Berlin and HU Berlin, spokesperson: Professor Dr. Bernd Hamm)
https://gepris.dfg.de/gepris/projekt/372486779
CRC Scaling Cascades in Complex Systems (FU Berlin, spokesperson: Professor Dr. Frank Noé) https://gepris.dfg.de/gepris/projekt/235221301
CRC Mechanisms and Disturbances in Memory Consolidation: From Synapses to Systems (HU Berlin, spokesperson: Professor Dr. Matthew Larkum)
https://gepris.dfg.de/gepris/projekt/327654276
CRC CROSSING – Cryptography-Based Security Solutions: Enabling Trust in New and Next Generation Computing Environments (TU Darmstadt, spokesperson: Professor Dr. Marc Fischlin) https://gepris.dfg.de/gepris/projekt/236615297
CRC/Transregio Heterogeneous Oxidation Catalysis in the Liquid Phase – Mechanisms and Materials in Thermal, Electro-, and Photocatalysis (University of Duisburg-Essen, spokesperson: Professor Dr. Malte Behrens; also applying: Universität Bochum)
https://gepris.dfg.de/gepris/projekt/388390466
CRC/Transregio Immune-Epithelial Communication in Inflammatory Bowel Diseases (University of Erlangen-Nuremberg, spokesperson: Professor Dr. Christoph Becker; also applying: Charité – FU Berlin and HU Berlin)
https://gepris.dfg.de/gepris/projekt/375876048
CRC/Transregio Mathematical Modelling, Simulation and Optimisation Using the Example of Gas Networks (University of Erlangen-Nuremberg, spokesperson: Professor Dr. Alexander Martin; also applying: HU Berlin, TU Berlin, TU Darmstadt)
https://gepris.dfg.de/gepris/projekt/239904186
CRC Adenine Nucleotides in Immunity and Inflammation (University of Hamburg, spokesperson: Professor Dr. Andreas H. Guse) https://gepris.dfg.de/gepris/projekt/335447717
CRC Integrative Analysis of Pathogen – Replication and Spread (University of Heidelberg, spokesperson: Professor Dr. Hans-Georg Kräusslich)
https://gepris.dfg.de/gepris/projekt/240245660
CRC Chemical Mediators in Complex Biosystems (ChemBioSys) (University of Jena, spokesperson: Professor Dr. Christian Hertweck) https://gepris.dfg.de/gepris/projekt/239748522
CRC/Transregio Light-Driven Molecular Catalysts in Hierarchically Structured Materials – Synthesis and Mechanistic Studies (University of Jena, spokesperson: Professor Dr. Sven Rau; also applying: University of Ulm)
https://gepris.dfg.de/gepris/projekt/364549901
CRC/Transregio Multiscale Simulation Methods in Soft Matter Systems (University of Mainz, spokesperson: Professor Dr. Friederike Schmid; also applying: TU Darmstadt) https://gepris.dfg.de/gepris/projekt/233630050
CRC Chemical Biology of Epigenetic Modifications (LMU Munich, spokesperson: Professor Dr. Thomas Carell) https://gepris.dfg.de/gepris/projekt/325871075
CRC/Transregio TRiPs to Homeostasis: Maintenance of Body Homeostasis by Transient Receptor Potential Channel Modules (LMU Munich, spokesperson: Professor Dr. Thomas Gudermann; also applying: University of Saarbrücken) https://gepris.dfg.de/gepris/projekt/239283807
CRC Atherosclerosis: Mechanisms and Networks of Novel Therapeutic Targets ( LMU Munich, spokesperson: Professor Dr. Christian Weber)
https://gepris.dfg.de/gepris/projekt/238187445
CRC Hearing Acoustics: Perceptual Principles, Algorithms and Applications (University of Oldenburg, spokesperson: Professor Dr. Volker Hohmann)
https://gepris.dfg.de/gepris/projekt/352015383
CRC Information Density and Linguistic Encoding" (University of Saarbrücken, spokesperson: Professor Dr. Elke Teich) https://gepris.dfg.de/gepris/projekt/232722074
CRC Molecular Heterogeneous Catalysis in Confined Geometries (University of Stuttgart, spokesperson: Professor Dr. Michael R. Buchmeiser)
https://gepris.dfg.de/gepris/projekt/358283783
Further Information
Media contact:
DFG Press and Public Relations, Tel. +49 228 885-2109, presse@dfg.de
The respective spokesperson of each Collaborative Research Centre can also provide additional information.
Contact at the DFG Head Office:
Dr. Suzanne Zittartz-Weber, Head of the Collaborative Research Centres, Research Centres, Clusters of Excellence Group,
Tel. +49 228 885-2304, suzanne.zittartz-weber@dfg.de
More detailed information on the funding programme and the Collaborative Research Centres to be awarded funding can be found here: