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Could a simple eye exam detect signs of Alzheimer’s disease?

Researchers at Massachusetts General Hospital and Brigham and Women’s Hospital in Boston have begun a study to find out. Dr. Gad Marshall, associate professor of neurology at Harvard Medical School, is testing a special retina camera and software developed by a Canadian startup to determine whether it can identify bits of amyloid plaques in the back of the eye that may indicate Alzheimer’s.

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Alzheimer’s, the most common form of dementia, can already be diagnosed with about 85% accuracy through positron emission tomography scans of the brain or by analyzing a sample of spinal fluid, Marshall said. But few patients get those tests; PET scans are costly and require the injection of a radioactive drug, while spinal taps involve the insertion of a needle into the spinal canal.

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