Alton defeated O'Fallon 5-3 Wednesday at O'Fallon.
Grace Presley struck out 15 in seven innings of work to pick up the win for Alton. Kennedy Clark was tagged with the loss for O'Fallon.
Alton (2-3) goes on the road to play Belleville East on Thursday at 4:30 p.m. O'Fallon (1-9) plays at home against Belleville West on Thursday.