Bad news, urbanites: Studies suggest that city populations have higher rates of mental illness than rural ones. In fact, urbanites have a 21% increased risk of developing an anxiety disorder and a 39% increased risk of having a mood disorder compared with residents of rural areas, according to a 2010 study.
Why do city dwellers have higher rates of mental illness? The answer could come down to how their brains process stress. For a 2011 study, researchers scanned the brains of urbanites and found increased activity in two brain regions: the amygdala, involved in processing emotions, and the perigenual anterior cingulate cortex, involved in processing stress.